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Very little went right for the Bills' quarterback in a tough contest on Thursday evening against the Texans.

And still he nearly managed to willing the Bills to a victory before an interception in the final minute sealed their fate in a close defeat.

The quarterback endured consecutive tackles for loss on the team's final possession, resulting in a long fourth down, but Buffalo (with seven wins) picked up significant yardage on a quick throw from Allen to Josh Palmer, who flipped a lateral to Khalil Shakir.

Following a false-start penalty created a fourth-and-6 for Buffalo, a Texans defender intercepted Allen’s pass at the 9-yard line with 24 seconds left.

We possessed a chance to win it there at the end,” Josh Allen stated. “We did a solid job of hanging tough and our defense saved us a couple of times. We’ve got find a way, and unfortunately we failed.”

Proved difficult for Allen to establish rhythm on a night he was brought down a career-high eight times and hit four other times. Allen passed for 253 passing yards with two interceptions and zero scores after accounting for six touchdowns in a victory over Tampa Bay last week.

Whenever they pressure our QB a dozen times, I don’t like that,” Bills coach Sean McDermott said. “I disapprove of that statistic at all. It is not a healthy way to compete and it’s not a good way to keep our field general healthy for the remaining games. We need to play better.”

Josh Allen was slow to get up after a tackle in the first half. He said he was fine and that his shoulder “went a little numb” after he fell on it awkwardly. He was questioned about being hit so many times during the game.

It's unpleasant,” he said. “I ran into a few personally. I’ve got to be more effective at throwing the ball away. On multiple occasions, I was going backwards.”

Allen lost 70 yards on the eight sacks. Anderson had two and a half sacks to lead the Houston defense. His second one came when he nearly sacked the QB near the scrimmage line, but he escaped and Anderson rose and chased him across the field to tackle him for an 18-yard deficit to force a punt early in the third.

Buffalo played for a second straight game absent receiver Keon Coleman after he was once more a non-participant after he was late to a squad gathering before their last game. He was previously benched for the first series of a defeat to New England in Week 5 after also being delayed for a team session.

No change. We are taking it one day at a time,” McDermott said. “I thought he had a improved week, but we are handling it step by step. It wasn’t that it wasn’t thought about, but we opted for the guys that provide the optimal opportunity.”

Khalil Shakir led the Buffalo with eight receptions for 110 receiving yards and James Cook had 116 rushing yards and a score.

The quarterback was frustrated that the team couldn’t execute down the stretch.

In the end, we must execute, and we didn’t succeed of that tonight,” he concluded. “Whatever situation and any condition, we’ve got to find a way, and we came up short.”